Mesoterapia vs. Microagulhamento: Mesoterapia mais eficaz que o microagulhamento?

Mesotherapy and microneedling are two common treatment modalities in the field of modern aesthetic medicine, each with its own unique principles and applications. But Which is More Effective for skin rejuvenation and targeted skin concerns?

What is Mesothrapy?

Mesotherapy, also known as intradermotherapy, is a minimally invasive treatment that involves injecting medications, vitamins, or other active substances directly into the middle layer of the skin. It was first developed by French physician Dr. Michel Pistor in 1952 and officially named “Mesoterapia” in 1958.

Mesotherapy uses microinjection techniques to target the mesoderm layer with conventional drugs, vitamins, minerals, amino acids, and other cellular nutrients to address localized issues. Initially used to treat joint pain and hearing disorders, it gradually expanded into areas such as skin rejuvenation, fat dissolution, and anti-aging. In 1987, the French Ministry of Health officially recognized it as a legitimate traditional medical treatment.

How Dose Mesothrapy Works?

The mechanism of action in mesotherapy involves both physical stimulation and chemical effects:

1. Physical stimulation: Multiple injections mechanically stimulate the skin, improving microcirculation, epidermal metabolism, and collagen remodeling, thereby promoting skin health.
2. Chemical effects: The injected medications directly enter the skin and exert their pharmacological actions, such as promoting local microcirculation and inducing the release of cell factors and growth factors related to hair growth.

Additionally, mesotherapy is characterized by being non-surgical, painless or minimally painful, and does not disrupt the integrity of the skin structure.

Types of Solutions in Mesotherapy:

Common solutions used in mesotherapy include local anesthetics (such as lidocaine), saline, and various drug cocktail formulas. These solutions typically need to be water-soluble, have an equal PH, and be clear and isotonic to ensure skin tolerance. Classic mesotherapy formulas may contain multiple components, but generally, a maximum of three antagonistic drugs are mixed to ensure safety and efficacy.

Mesotherapy utilizes various mechanisms and solution types to achieve its widespread applications in skin rejuvenation and disease treatment. Its long history and continuous development make it an important component of modern aesthetic medicine.

Type of Mesotherapy Machine

Type of Mesotherapy Machine	Descrição	Exemplos
Needle-based Machines	– Pen-like devices with single or multiple micro-needles. – Deliver targeted injections with adjustable depth and frequency.	– Professional Dermashine machine – Professional mesotherapy gun injector
Needle-free Machines	– Utilize electroporation technology for non-invasive delivery. – Use micro-currents to nourish and stimulate skin cells.	– Hydro Facial 14 in 1 with microneedling – Professional needleless mesotherapy injector M6
Combination Machines	– Combine mesotherapy with other technologies for enhanced treatment. – Offer multiple functions such as microdermabrasion, cold therapy, and RF.	– 3 in 1 microdermabrasion machine – Professional cold therapy machine D COOL – Professional mesotherapy NANO + RF + EMS device

Mesotherapy devices vary widely in their design and application, from traditional injection machines to advanced needle-free systems and multifunctional devices that combine various treatment modalities. Each type of device is tailored to deliver specific active ingredients effectively, catering to different skin concerns and patient needs.

What is Microneedling?

Microneedling, also known as percutaneous collagen induction therapy (PCIT), is an emerging medical technique that uses fine needle-like instruments to mechanically or physically micro-injure and stimulate the skin to achieve therapeutic or cosmetic effects. Archaeological findings suggest that the Zhuang ethnic minority in Guangxi, China, was one of the earliest civilizations to use needle therapy for medical purposes, with bronze shallow needles discovered in a late Western Zhou Dynasty tomb in Matou Town, Wuming County, Guangxi.

How Dose Microneedling Works?

The primary mechanisms of action in microneedling include:

1. Enhanced transdermal drug penetration: Microneedles create microscopic channels in the skin, enhancing the transdermal penetration and absorption of macromolecular drugs.
2. Triggering wound healing mechanisms: The physical stimulation of microneedles does not damage the overall skin structure but triggers the natural healing and repair process, promoting the release of fibroblast growth factor (FGF), platelet-derived growth factor (PDGF), and transforming growth factor (TGF).
3. Improving skin appearance and texture: When used for facial rejuvenation, microneedling stimulates the natural healing process and enhances the transdermal absorption of subsequent active ingredients, thereby improving skin appearance and texture.
4. Local drug delivery route: Microneedle devices consist of hundreds of microneedles arranged on a small patch, penetrating the stratum corneum and bypassing the barrier layer to deliver drugs directly into the epidermis or dermis, then entering systemic circulation, demonstrating therapeutic effects.

Types of Microneedle Devices:

Based on different classification criteria, microneedle devices can be divided into various types:

Tipo de dispositivo	Descrição	Usos comuns	Exemplos
Solid Microneedles – Rolo derma	Handheld device with multiple tiny needles arranged in a roller.	At-home skin treatments, product absorption	Original Dermaroller, Dr. pen Dermaroller, ZGTS 192 Needles
Hollow Microneedles – Caneta Dermatológica	Automated device with a vibrating tip containing multiple microneedles for precise penetration.	Professional treatments, skin rejuvenation	Dr. Pen, Rejuvapen
Polymer Microneedles – Carimbo de derma	Stamp-like device with microneedles for targeted treatment of specific areas.	Treating hard-to-reach spots, localized issues	Aquagold, Dr. pen 140A
Coated Microneedles – Fractional Radiofrequency Microneedling	Combines microneedling with radiofrequency energy to stimulate deeper skin layers.	Skin tightening, reducing acne scars	Morfeu8, M8 Pro, M8 Pro Plus, M8 Pro Max
Hydrogel microneedles – Caneta Hidro	Wireless microneedling device that incorporates serum into the needle cartridge for enhanced treatment.	Skin rejuvenation, boosting product absorption	Dr. Pen Hydra Pen H2, H3

Efficacy of Mesotherapy in Aesthetic Medicine

Mesotherapy is recognized for its multiple benefits in aesthetic medicine, particularly in anti-aging, skin rejuvenation, localized fat reduction, and cellulite elimination. Here is a detailed analysis of its effects supported by clinical research.

Mesotherapy has proven to be particularly effective for skin rejuvenation. By injecting a variety of nutrients such as non-crosslinked hyaluronic acid, platelet-rich plasma (PRP), vitamins, trace elements, and minerals, mesotherapy enhances skin hydration, stimulates fibroblast activity, and regulates the expression of matrix metalloproteinases and their inhibitors. This process promotes collagen and elastin synthesis, resulting in firmer and smoother skin. The treatment not only improves skin tone but also enhances elasticity and radiance. Thereby achieving anti-aging and skin remodeling effects.

Comparison with Other Skin Treatments

Compared to other skin treatments, mesotherapy offers unique advantages. For example, while radiofrequency treatments focus on lifting and tightening the skin, needle-free mesotherapy primarily targets wrinkles, hydration, and skin brightening. Mesotherapy effectively penetrates the skin barrier, allowing active ingredients to reach targeted areas, and it utilizes the skin’s ability to store and release medications, achieving significant effects with minimal dosages. Furthermore, mesotherapy can be combined with other aesthetic procedures such as intense pulsed light, red light therapy, and low-energy radiofrequency to enhance treatment outcomes.

In summary, mesotherapy is an innovative skin rejuvenation technique that directly delivers various active substances to the deeper layers of the skin, effectively addressing skin concerns and achieving rejuvenation goals. Although research on its mechanisms and active ingredients is still developing, its clinical applications have gained widespread recognition and validation.

Efficacy of Microneedling in Aesthetic Medicine

Microneedling is another prominent technique in aesthetic medicine, known for its ability to improve skin texture, reduce wrinkles, eliminate pigmentation, enhance skin elasticity, and promote collagen production.

Numerous studies have shown that microneedling can effectively improve skin conditions. Research indicates that microneedling stimulates the skin’s natural healing response, promoting regeneration. Additionally, microneedling enhances collagen synthesis, improving skin texture and elasticity. These findings underscore microneedling’s significant effectiveness in the field of aesthetics.

Benefits of Microneedling for Skin Rejuvenation

Microneedling excels in facial rejuvenation. By introducing collagen-inducing serums into the skin, microneedling significantly enhances the youthful appearance of facial skin. The combination of microneedling with radiofrequency energy (Radiofrequency Microneedling, RFMN) further boosts collagen and elastin production, improving skin texture and tightness. This comprehensive approach not only enhances efficacy but also reduces recovery time, allowing patients to see noticeable results quickly.

Comparison with Other Skin Treatments

When compared to traditional chemical peels and laser treatments, microneedling presents several advantages. Notably, microneedling does not damage the epidermis, resulting in fewer side effects and faster recovery. It utilizes physical stimulation rather than chemical or thermal means, minimizing the risk of irritation and thermal injury. Additionally, microneedling is straightforward to perform, with readily available equipment, making it suitable for widespread application.

In conclusion, microneedling is widely used in the field of skin aesthetics due to its safety, effectiveness, and convenience. It has demonstrated favorable outcomes in clinical studies, making it a viable option for individuals seeking natural and non-invasive skin care alternatives.

Potential Side Effects and Risks of Mesotherapy

While mesotherapy offers various benefits in aesthetic medicine, such as skin rejuvenation, fat reduction, and cellulite treatment, it is not without potential side effects and risks. Here is a detailed analysis of the common side effects and associated risks:

Common Side Effects of Mesotherapy

1. Dor: Due to the injection process, some pain may occur. The level of pain depends on the type of needles used.
2. Erythema and irritation: Mild and transient side effects like erythema, irritation, dryness, and scaling may occur during the treatment.
3. Hypopigmentation: There have been rare reports of two cases of hypopigmentation.
4. Edema and ecchymosis: Immediate post-treatment erythema, edema, ecchymosis, or small wheals may occur to varying degrees.

Potential Risks Associated with Mesotherapy

1. Skin injury and infection: Improper technique can lead to skin and mucosal injury, increased secretion, and bleeding. Poor aftercare can also lead to bacterial infection.
2. Anaphylactic shock: When using certain drugs (e.g., Peridil Heparine), immediate and significant local erythema may occur, potentially leading to acute drug-induced anaphylactic shock.
3. Foreign body granuloma: Although rare, TA (sodium hyaluronate) administered via mesotherapy may potentially cause foreign body granulomas.

Safety Precautions for Mesotherapy Treatment

1. Postoperative care:

• Avoid wetting the skin: The skin surface will have tiny wounds after mesotherapy. Avoid wetting the area for 24 hours to prevent bacterial infection.
• Sun protection: Wear a hat or umbrella when going out to avoid strong light exposure.
• Avoid high-temperature environments: For three days, avoid saunas, strenuous exercise, and excessive sweating.
• Light diet: Avoid spicy foods, coffee, alcohol, and other irritating foods and beverages.
• No makeup: Avoid makeup for some time, especially functional cosmetics and skincare products for the first three days.

2. Choose a reputable institution: It is best to undergo treatment at a reputable hospital’s dermatology or aesthetic department to ensure safety and efficacy.

3. Strict disinfection: Maintain strict disinfection throughout the process and use appropriate care products to avoid cutting corners for cost savings.

Mesotherapy has certain side effects and potential risks, but by following proper postoperative care and choosing a reputable institution for treatment, these risks can be effectively reduced to ensure safety and efficacy.

Potential Side Effects and Risks of Microneedling

Microneedling is a technique that uses tiny needles to penetrate the skin, promoting drug penetration and skin repair. However, despite its aesthetic and therapeutic benefits, it still carries some side effects and potential risks.

Common Side Effects of Microneedling

1. Bleeding and hematoma: Due to skin irritation, bleeding and hematoma may occur.
2. Infecção: If disinfection is inadequate or the procedure is performed improperly, skin infection can occur.
3. Allergic reaction: Some patients may develop an allergic reaction to the microneedles or the medications used.
4. Dor: Patients may experience pain during the treatment, especially without anesthesia.
5. Erythema and edema: This is a natural skin reaction to microneedle stimulation and usually subsides within a few days.
6. Hiperpigmentação: Including age spots and discoloration, this may be due to abnormal pigment metabolism after trauma.

Potential Risks Associated with Microneedling

1. Cicatrizando: Improper technique can lead to scarring.
2. Persistent granuloma: In some cases, microneedling may lead to persistent granulomatous lesions.
3. Abscess: Especially in the presence of open wounds or inflammation, using microneedles can easily lead to abscess formation.
4. Facial expression stiffness: Improper operation can potentially damage facial nerves, leading to facial expression stiffness.
5. Expensive equipment and high maintenance costs: New microneedles are required for each treatment, resulting in higher costs.

Safety Precautions for Microneedling

1. Choose a reputable medical institution: Microneedling should be performed at a qualified medical institution by professional personnel to reduce risks.

2. Preoperative preparation: Before treatment, avoid using irritating skincare products. If necessary, apply a topical anesthetic cream 30-60 minutes in advance to reduce pain.

3. Postoperative care:

• Avoid touching or rubbing the skin to prevent epidermal damage and avoid dryness, roughness, and redness.
• Avoid high-temperature environments like saunas or hot baths to prevent infection and accelerate recovery.
• Avoid spicy foods and alcoholic beverages for 7 days to reduce local bleeding and bruising.

4. Strict disinfection: Ensure that all instruments and medications used are thoroughly disinfected to prevent infection.

5. Follow operating standards: Strictly follow the “Microneedling Operating Specifications” to improve safety and efficacy.

While microneedling offers aesthetic and therapeutic benefits, its side effects and potential risks cannot be ignored. When choosing microneedling treatment, it is crucial to carefully consider and follow proper operating standards and postoperative care measures to ensure safety and efficacy.

When comparing the cost factors of mesotherapy and microneedling, several aspects must be considered, including the cost per treatment, overall treatment expenses, and long-term cost-effectiveness.

Cost Factors of Mesotherapy

1. Cost per Treatment: On average, a single mesotherapy session in the United States ranges from $250 to $600, with some paying as much as $2,500 per session, depending on the chosen clinic and the expertise of the practitioner.
2. Overall Treatment Costs: Mesotherapy often requires multiple sessions to achieve optimal results, making the total treatment cost an important consideration. The number of sessions and associated costs can vary based on individual needs.
3. Long-term Cost-effectiveness: The anticipated growth of the mesotherapy market in regions like the Middle East and Africa suggests that its cost-effectiveness may become more apparent over time.

Cost Factors of Microneedling

1. Cost per Treatment: Prices can vary widely depending on the cost of living in different areas. Urban centers typically have higher treatment costs compared to rural areas. Different types of microneedling (e.g., traditional microneedling, RF microneedling, or microneedling with PRP) have varying costs. For example, RF microneedling is generally more expensive due to the technology used.
2. Overall Treatment Costs: Similar to mesotherapy, microneedling also requires a series of treatments to achieve desired results, meaning that the total cost increases with the number of sessions.
3. Equipment and Material Costs: The manufacturing cost of hydro pen is usually higher than that of derma rollers due to the need for specialized equipment and materials.

Long-term Cost-effectiveness Analysis

1. Mesoterapia: Although the cost per treatment is relatively high, the expected growth in markets like the Middle East and Africa may enhance its long-term cost-effectiveness.
2. Microagulhamento: If microneedling proves to be more effective and cost-efficient compared to other standard treatments, it may offer better long-term value. Additionally, the mass production of microneedling technology indicates a strong potential for cost-effectiveness.

Suitable Skin Conditions for Each Treatment

Conditions Suitable for Mesotherapy

1. Enlarged Pores: Mesotherapy can effectively improve the appearance of enlarged pores.
2. Pele seca: This treatment shows significant results for dry skin conditions.
3. Problemas de pigmentação: Mesotherapy is effective in addressing pigmentation and discoloration problems.
4. Uneven Skin Texture: It can promote cellular regeneration to improve uneven skin caused by inflammation or long-term acne.
5. Wrinkles, Dullness, and Scars: Mesotherapy provides good results for these skin concerns.

Conditions Suitable for Microneedling

1. Pele sensível: Microneedling can improve sensitive skin without causing excessive irritation.
2. Acne and Acne Scars: This treatment helps induce healing and improve the appearance of acne scars.
3. Wrinkles and Melasma: Microneedling can reduce the appearance of wrinkles and melasma.
4. Skin Texture and Elasticity: It continuously promotes collagen regeneration, improving skin texture and elasticity.
5. Superficial Tumors and Wounds: Microneedling can be used to treat various skin conditions, including superficial tumors and wounds.

Customized Treatment for Specific Skin Issues

1. Planos de tratamento personalizados: Institutions like the Nanjing Skin Disease Research Institute develop tailored treatment plans based on individual skin types, symptoms, disease stages, and pathological characteristics.
2. Customized Solutions: Brands like FILLMED emphasize “customized solutions” that target specific skin issues based on individual skin characteristics.
3. Comprehensive Care Approach: The Lin Ting brand utilizes a three-dimensional skincare system that combines professional consultations, instrument testing, and customized solutions to help individuals with problematic skin regain confidence.

Both mesotherapy and microneedling have their respective cost factors and long-term cost-effectiveness. Mesotherapy tends to have a higher cost per treatment but offers promising long-term benefits, while microneedling is generally more affordable per session but may require multiple treatments. Each method is suited for different skin conditions, and personalized treatment plans can effectively address specific skin issues.

In comparing mesotherapy and microneedling, we can analyze various aspects, including recovery times, patient satisfaction, and expert opinions on both treatments.

Recovery Times After Treatment

Mesotherapy Recovery Time:

• Mesotherapy requires proper post-treatment care to prevent inflammation or infection, indicating a recovery period.

Microneedling Recovery Time:

• Post-treatment care for microneedling includes avoiding water on the treated area for 8 hours, refraining from using daily skincare products for 1-3 days, and avoiding cleansers and makeup for 3-5 days. This suggests a short recovery period, typically within a few days.
• The patients can resume normal activities quickly, but the detailed aftercare guidelines indicate that attention is still needed during the recovery phase.

Importance of Post-Treatment Care

• Both treatments emphasize the necessity of post-treatment care to achieve optimal results. For microneedling, specific aftercare instructions include using sterile moisturizing masks and anti-inflammatory medications to ensure effective recovery and minimize side effects.

Patient Satisfaction and Recommendations

Mesotherapy Patient Satisfaction:

• In the Petaling Jaya area, mesotherapy has received high patient satisfaction ratings, with an average score of 9.8 from 786 verified reviews. The accreditation of all doctors by the Malaysian Ministry of Health enhances trust and credibility.

Microneedling Patient Satisfaction:

• Most customers are satisfied with the results.

Expert Opinions on Mesotherapy and Microneedling

Mesoterapia

• Mesotherapy is widely recognized in dermatology for its effectiveness in improving skin barrier function, reducing inflammation, and promoting skin repair. Studies have shown significant improvements in conditions like rosacea and severe acne when combined with products like NCTF. However, results can vary based on individual differences, necessitating personalized adjustments to treatment plans.

Microagulhamento

• Microneedling has gained traction for its ability to enhance absorption of active ingredients and stimulate collagen production. Experts appreciate its simplicity and cost-effectiveness, particularly for treating scars, acne, stretch marks, and wrinkles. However, they caution that the skin barrier may become vulnerable post-treatment, highlighting the importance of timely care to prevent external irritants from causing issues.

Combined Therapies

Both mesotherapy and microneedling can be effectively combined with other treatments to enhance results:

• Mesoterapia can be paired with PDO thread lifts, botulinum toxin, and laser treatments to improve skin appearance and texture.
• Microagulhamento can be combined with topical treatments like 5-fluorouracil for conditions like vitiligo or with PRP injections for scar treatment, demonstrating its versatility.

Both mesotherapy and microneedling have their respective recovery periods and post-treatment care requirements. Mesotherapy shows high patient satisfaction in certain regions, while microneedling lacks specific satisfaction data. Expert opinions on both treatments highlight their effectiveness and the importance of personalized care. Additionally, combining these treatments with other modalities can enhance their efficacy and patient outcomes.

When choosing between mesotherapy and microneedling, several factors must be considered, including skin health, sensitivity, treatment goals, and specific patient needs.

Factors in Choosing Mesotherapy vs. Microneedling

Skin Type and Sensitivity:

• For sensitive skin, it is advisable to start with a soothing repair kit and gradually introduce other active ingredients based on the skin’s condition.
• The depth of penetration in microneedling should also be adjusted according to skin sensitivity. Initially, needles ranging from 0.3 to 1.0 mm can be used, with the option to alternate to 1.5 mm needles later.

Objetivos de tratamento:

• Mesotherapy is suitable for a variety of skin issues, such as hair loss and pigmentation disorders, and can be used alone or in conjunction with other aesthetic treatments.
• Microneedling primarily targets acne atrophic scars, melasma, and other cosmetic concerns. Its effectiveness depends on pre-treatment preparation, combined therapies, and multiple treatment sessions.

Physical Parameters and Drug Properties:

• The transdermal efficiency of microneedling is influenced by the patient’s skin health, the physical parameters of the needles, and the properties of the mesotherapy drugs.
• The depth of needle penetration is not the only determining factor; different treatment areas may require different needle lengths to ensure comfort and effectiveness.

Planos de tratamento personalizados

Personalized medicine involves designing the best treatment plan based on a patient’s genomic information, proteomics, metabolomics, and other relevant internal environmental data, aiming to maximize treatment effectiveness and minimize side effects. For instance, individualized treatment plans can be developed using ATP tumor drug sensitivity tests to select the most effective chemotherapy drugs or combinations for a patient.

When selecting between mesotherapy and microneedling, it is essential to consider factors such as skin type, sensitivity, treatment goals, and physical parameters. Consulting with professional skincare experts can provide personalized treatment recommendations and plans. Furthermore, adopting personalized treatment strategies can better meet patients’ specific needs, enhance treatment outcomes, and reduce side effects.

Conclusão

Key Points in Comparing Mesotherapy and Microneedling

Comparison Point	Mesoterapia	Microagulhamento
Mecanismo	Involves injecting a cocktail of vitamins, hyaluronic acid, and growth factors into the dermis and subcutaneous tissue to hydrate skin and increase cell regeneration	Uses multiple ultrafine needles to create micro-wounds in the skin, stimulating a healing response that produces new collagen and elastin
Tipo de agulha	Single, superfine needle that penetrates below the dermis	Multiple ultrafine needles that penetrate the dermis
Skin Penetration Depth	Targets the middle layer (dermis) and subcutaneous tissue	Targets the first layer (epidermis), but can also reach the dermis with modern techniques
Skin Conditions Treated	Fine lines, cellulite, sagging skin, uneven skin tone	Acne scarring, deeper signs of aging, texture-related concerns
Needle Length	Longer needles due to deeper penetration	Shorter needles
Velocidade de tratamento	Faster with a mesogun compared to a single injection	Faster with an automatic microneedling pen
Propósito	Improve general skin health, reduce signs of aging	Skin rejuvenation, reduce scarring, lighten hyperpigmentation, treat hair loss, wrinkles and fine lines
Tempo de inatividade	Some downtime due to injection	Little to no downtime

Mesotherapy:

1. Mechanism and Ingredients: Mesotherapy primarily involves intradermal injection of various nutrients like hyaluronic acid and amino acids to increase skin hydration, activate fibroblasts, and regulate the expression of matrix metalloproteinases and their inhibitors.
2. Aplicativos: It is widely used for facial rejuvenation, hair growth stimulation, fat dissolution, treatment of pigmentation disorders, and sensitive skin.
3. Efficacy: Studies show mesotherapy is effective in treating pigmentation disorders, though the exact mechanism is still unclear. Some research indicates it can significantly improve epidermal and dermal thickness, thereby reducing the visibility of pigmentation. Additionally, mesotherapy demonstrates better results than traditional medications in treating androgenetic alopecia.
4. Satisfação do Paciente: Due to its non-invasive nature and relatively high safety profile, patient satisfaction with mesotherapy is high.

Microease:

1. Mechanism and Technique: Microneedling uses sterile microneedles to repeatedly pierce the skin, disrupting the connecting scar tissue collagen in the dermis and promoting skin regeneration and collagen production.
2. Aplicativos: It is widely used to treat atrophic scars, melasma, and facial photodamaging skin conditions.
3. Efficacy: Multiple studies have proven the effectiveness of microneedling in various skin conditions, such as melasma, acne scars, and facial photodamage. Furthermore, combining microneedling with radiofrequency energy can significantly enhance collagen and elastin production, resulting in tighter, more youthful skin.
4. Safety and Recovery: Microneedling is minimally invasive, preserving the local integrity of the epidermis, with a shorter recovery period and lower risk, making it relatively safer.

Mesotherapy more effective than microneedling?

Mesotherapy:
Mesotherapy has a wide range of applications in aesthetic dermatology, particularly in treating pigmentation disorders and androgenetic alopecia, where it shows some advantages.

Microease:
As a minimally invasive technique, microneedling demonstrates good efficacy and relatively high safety in treating various skin conditions. By stimulating skin regeneration and collagen production, it can effectively improve skin condition.

Overall, both treatments have their own advantages and suitable applications. The choice between them should be personalized based on the specific condition and patient needs.

Perguntas frequentes

1. What is the main difference between mesotherapy and microneedling?
   Mesotherapy (Mesotherapy) and microneedling are essentially the same treatment method with different tools. Mesotherapy was initially developed to inject medications into the subcutaneous fat layer, but is now used in cosmetic surgery to combat skin aging. Microneedling, on the other hand, uses a microneedle roller with ultra-fine needles to directly deliver highly nutritious active ingredients to the desired skin tissue, allowing the skin to absorb and act quickly, activating cells and promoting skin metabolism.
2. Are mesotherapy and microneedling painful procedures?
   Microneedling typically creates a temporary channel on the skin surface, causing only mechanical stimulation to the skin without inducing inflammatory heat damage. Therefore, microneedling is relatively gentle, but there is still some pain. If patients are very sensitive to pain, needle-free injection devices can be used for treatment, which is almost painless and rarely causes bruising, redness, or swelling.
3. How many treatment courses are usually needed to achieve optimal results with mesotherapy and microneedling?
   Mesotherapy and microneedling usually require around 3 to 5 treatments to be effective, with the specific number determined by the patient’s skin condition. Mesomicroneedling can be performed every 2-4 weeks, depending on the chosen product and the local wound healing time.
4. Can mesotherapy and microneedling be combined with other skincare therapies?
   Mesotherapy and microneedling can be combined with other aesthetic techniques, such as intense pulsed light, red light, and low-energy radiofrequency. This combination therapy can enhance the effect and prolong the duration.
5. Are mesotherapy and microneedling suitable for all skin types?
   Mesotherapy and microneedling are suitable for most skin types, including sensitive skin. However, for certain specific skin problems like acne scars and pigmentation, both treatments have significant effects. Nevertheless, whether they are suitable or not depends on the individual’s skin condition and the doctor’s recommendation.

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