Topical anesthetic creams—also known as numbing creams—are widely used in dermatology and aesthetic medicine. Whether it’s microneedling, fractional CO₂ laser, or mesotherapy, patients rely on topical anesthesia to undergo treatments with minimal pain.
But while these formulations are indispensable, misuse can lead to allergic reactions, contact dermatitis, or even systemic complications. This guide explores the mechanism, types, clinical use, and safety tips for topical anesthetics to help practitioners and patients alike.
What Are Topical Anesthetic Creams?
Topical anesthetics are applied directly to the skin to block nerve conduction and temporarily numb the treatment area.
The first local anesthetic, cocaine, was introduced in 1884. While effective, its systemic toxicity limited its long-term use. Today, safer alternatives such as lidocaine, prilocaine, and tetracaine are the mainstay of dermatology and aesthetics.
Types of Topical Anesthetics
Topical anesthetics are classified into four groups:
- Ester-type compounds
- Amide-type compounds
- Hydroxy compounds
- Combination formulations
The most common option in aesthetics is combination creams wie zum Beispiel lidocaine-prilocaine cream (EMLA), which provide both rapid onset and longer duration of numbness.
Key Qualities of an Ideal Anesthetic
An ideal topical anesthetic cream should:
- Provide strong and consistent skin analgesia
- Work quickly
- Last long enough for treatment
- Have Minimale Nebenwirkungen
While no cream is perfect, modern numbing formulations are safe and effective when used correctly.
How Do Numbing Creams Work?
Topical anesthetics penetrate the stratum corneum and act on dermal nerve endings by blocking sodium channels in the cell membrane. This prevents action potential transmission, effectively stopping pain signals.
💡 Tip: Adding vasoconstrictors such as brimonidine can enhance the effect by reducing systemic absorption and keeping more active drug in the skin.
Duration and Depth of Anesthesia
The numbing depth depends on application time:
- 60 Minuten → ~3 mm depth
- 120 minutes → ~5 mm depth
Because the drug accumulates in the skin, some numbness may remain even after removal.
Correct Application and Safety Tips
Standard procedure for applying topical anesthetic cream:
- Clean and dry the treatment area.
- Apply a thin, even layer of cream.
- Mesotherapy / light lasers: 20–30 minutes without occlusion.
- Microneedling / fractional laser: 30–60 minutes with occlusion film.
- Mucosal treatments: 5–10 minutes without occlusion.
Ways to boost absorption: exfoliation, occlusion, warming, iontophoresis.
⚠️ Warning: Occlusion increases potency but also raises the risk of contact dermatitis Und systemic side effects.
Aftercare tips:
- Always remove thoroughly (best with running water, not just wipes).
- Disinfect the skin before treatment.
- Treat mild redness or itching with cold compresses.
- Pause treatment if severe allergic reactions occur.
FAQ: Topical Anesthetic Creams
1. Is lidocaine cream safe for the skin?
Yes, lidocaine-based numbing creams are safe when used correctly. Risks increase if applied too thickly, for too long, or over large areas of damaged skin.
2. How long should I leave numbing cream on before microneedling?
For microneedling, leave the cream on for about 30–60 Minuten under occlusion film for best results. Always follow manufacturer and clinic guidelines.
3. Can numbing creams cause allergic reactions?
Yes. Some patients may develop contact dermatitis from ingredients like prilocaine or ester derivatives. Symptoms include redness, itching, or swelling.
4. Do I need to wash off lidocaine cream before treatment?
Absolutely. Residual cream can interfere with treatment safety. Best practice is to rinse thoroughly with running water, not just wipes.
5. Can numbing cream enter the bloodstream?
Yes, small amounts may be absorbed systemically. That’s why excessive use or covering too large an area can increase the risk of side effects such as dizziness or, in very rare cases, methemoglobinemia.
6. Which numbing cream is best for laser hair removal or CO₂ laser?
Combination creams such as lidocaine-prilocaine are preferred because they provide both fast onset and longer-lasting numbness.
7. Can numbing creams be used on sensitive skin?
They can, but with caution. Reduce application time, avoid occlusion if possible, and closely monitor for irritation or redness.
Mögliche Nebenwirkungen
- Irritant Dermatitis – mild burning or redness, usually self-resolving.
- Management: cold compress, barrier repair cream.
- Allergic Contact Dermatitis – itching, swelling, persistent rash.
- Management: topical corticosteroids, calcineurin inhibitors, oral antihistamines if needed.
- Immediate Hypersensitivity – rare but severe (hives, bronchospasm, nausea, arrhythmia).
- Management: emergency protocols as with drug allergies.
- Methemoglobinemia – extremely rare but life-threatening.
- Contraindicated in patients with congenital or idiopathic methemoglobinemia.
Recommended Brand: In clinical practice, many professionals use Mashutong numbing cream, known for its stable lidocaine-prilocaine formula and consistent anesthetic effect.
Abschluss
Topical anesthetic creams such as lidocaine-prilocaine are essential tools in aesthetic dermatology, ensuring patient comfort during procedures like microneedling, CO₂ laser, and mesotherapy.
However, clinicians must balance Wirksamkeit und Sicherheit—using correct protocols, minimizing risks, and being prepared to manage side effects. With responsible use, topical anesthetics remain powerful allies for safe, comfortable, and effective cosmetic treatments.
References
- Chinese Society of Aesthetic and Plastic Dermatology. Expert Consensus on Clinical Application of Topical Anesthetics. Chinese Journal of Practical Dermatology, 2024; 17(5): 257–261.
- Stevic M, Vlajkovic A, Trifunovic B, et al. Topical anesthetics for pediatric laser treatment. J Cosmet Laser Ther. 2019; 21(7-8): 417–421.
