When it comes to professional tattoo removal, two technologies dominate the field — Pico Laser and Fractional CO₂ Laser. Both are powerful tools, but they work in different ways and are suited for different stages of treatment. As a certified manufacturer of advanced aesthetic devices, Mico Aes explains how these two lasers complement each other for superior tattoo clearance and skin recovery.

Understanding Pico Laser: Fast, Precise, and Gentle
The Pico Laser uses ultra-short picosecond pulses (1 trillionth of a second) to shatter pigment particles into microscopic fragments via a photoacoustic effect. This means less heat, minimal tissue damage, and reduced risk of post-inflammatory pigmentation.
- Targets black, blue, and green pigments effectively
- Minimal downtime — only 1–3 days of redness or mild swelling
- Requires fewer sessions (3–6 on average)

Understanding CO₂ Laser: Repair and Resurface the Skin
The Fractional CO₂ Laser operates with 10,600 nm wavelength, creating controlled microthermal zones that stimulate collagen remodeling and epidermal regeneration. It’s ideal for treating scarring, uneven texture, and residual pigmentation after pigment removal.
- Improves skin smoothness and tone
- Promotes new collagen and tissue regeneration
- Best for skin recovery and texture refinement post-tattoo removal

Pico Laser vs CO₂ Laser: Key Differences
| Feature | Pico Laser | Fractional CO₂ Laser |
|---|---|---|
| Working Principle | Photoacoustic — shatters pigments without heat | Photothermal — vaporizes and resurfaces tissue |
| Main Target | Deep dermal tattoo pigments | Surface skin irregularities and scars |
| Downtime | 1–3 days | 5–7 days |
| Best For | Removing dark inks with minimal heat | Improving skin texture and healing post-removal |
The Ideal Approach: Combination Therapy
Instead of choosing one, leading dermatologists now use a combination of Pico and CO₂ lasers for tattoo removal:
- Step 1: Pico Laser breaks down deep pigment particles.
- Step 2: Fractional CO₂ Laser stimulates collagen and resurfaces the skin.
This synergy improves pigment clearance by up to 50% and shortens recovery time, according to the 2023 Journal of Laser Dermatology. It’s a powerful, science-backed approach for smoother, clearer, and healthier skin.

Why Choose Mico Aes Tattoo Removal Machines?
Mico Aes is a certified ISO13485, CE, FDA manufacturer specializing in professional tattoo removal machines. Our advanced Picoway Laser and Fractional CO₂ Laser systems offer superior stability, customizable parameters, and reliable after-sales support. Whether you’re a clinic, spa, or beauty equipment distributor, our technologies help you expand your service range and attract more clients.
Frequently Asked Questions
Which laser removes tattoos more effectively?
Pico Laser is more effective for deep pigment removal, while Fractional CO₂ Laser improves surface healing and reduces scarring. Combining both offers optimal results.
How many sessions are needed for complete tattoo removal?
Typically, 3–6 Pico Laser sessions are needed. Adding CO₂ Laser treatment can enhance results and improve skin texture between sessions.
Is the treatment safe for all skin types?
Yes. Both Pico and CO₂ lasers from Mico Aes are clinically tested and safe when operated by trained professionals with proper parameters.







